The “best” domain extension really depends on the specific needs and goals of your website. Here are some factors to consider:

Purpose of the website: If your website is for a business, then a .com extension may be the most appropriate choice since it is the most widely recognized and used extension for commercial websites. If your website is for an organization or a non-profit, then a .org extension may be a better fit.
Geographic location: If you are targeting a specific geographic location, then a country-specific domain extension like .us or .ca may be more appropriate.
Branding: If you want your domain name to be part of your branding strategy, then a unique domain extension like .io or .me may help you stand out from the crowd.
SEO: Some studies suggest that domain extensions do not directly affect search engine rankings, but having a relevant and memorable domain name can help with SEO.
Overall, it’s important to choose a domain extension that aligns with your website’s purpose and helps you achieve your goals.